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Animal Medicine Oxytetracycline I...
2024-05-14
KX-OXYTETRACYCLINE 20%
Oxytetracycline 20% Injection
COMPOSITION
Each ml contains oxytetracycline 200mg
PHARMACOLOGICAL ACTIONS
Oxytetracycline is a bacteriostatic antibiotic. It exerts its action by inhibiting the protein
synthesis of the bacterial cell. Inhibition of bacterial protein synthesis results in disturbance
of all functions necessary for the life of bacteria, especially cell- division, and the formation
of the cell wall are impaired.
TARGET SPECIES
Cattle, sheep, goats and pigs.
INDICATIONS
Oxytetracycline is an antimicrobial agent that is effective in the treatment of a wide range of
diseases caused by susceptible gram-positive and gram-negative bacteria, rickettsia and
mycoplasma, like respiratory, intestinal, dermatological, genitourinary and septicemic
infections in cattle, sheep, goats, pigs etc.
For cattle: Bronchopneumonia and other respiratory infections, infections of the
gastrointestinal tract, metritis, mastitis, septicaemia, puerperal infections, secondary
bacterial infections primarily caused by virus, etc.
For sheep and goats: Infections of respiratory, urogenital, gastrointestinal tract and hooves,
mastitis, infected wounds, etc.
ADMINISTRATION AND DOSAGE
By intramuscular injection.
Cattle, sheep, goats and pigs: 10- 20mg/kg (0.05- 0.1ml/ kg ) body weight once or
repeat after 48hours when necessary.
CONTRAINDICATIONS
Do not use in animals with known hypersensitivity to the active ingredient or excipients. Use
cautiously in young animals because teeth discoloration is possible.
Don't administer more than 20ml in cattle, 10ml in pigs, 5ml in calf, sheep and goats per
injection site.
USE DURING PREGNANCY, LACTATION OR LAY
The use of Oxytetracycline Injection during the period of tooth development
including late Pregnancy may lead to discoloration.
ADVERSE REACTIONS (FREQUENCY)
Tetracyclines may cause renal tubular necrosis at high doses, but this is rare with
recommended doses. Tetracyclines can affect bone and teeth formation in young animals.
Hepatoxicity may occur at high doses in susceptible individuals.
Oxytetracycline administration to horses has been associated with colic and diarrhea.
Anti metabolic effect. Tetracycline drugs can cause nitrogenemia, and can be aggravated
by the presence of steroid drugs.
These drugs can also cause metabolic acidosis and electrolyte imbalance.
CLINICALLY SIGNIFICANT DRUG INTERACTIONS
Do not dilute. It is unwise to administer bacteriostatic and bactericidal antibiotics
concurrently. This product should be avoided using with penicillin at the same time.
SYMPTOMS AND TRENTMENT OF OVERDOSAGE
Oxytetracycline has a wide margin of safety in the target species and overdosing is
unlikely to produce toxic symptoms.
WARNINGS
Horse can sometimes develop gastroenteritis after injected of this product, so it
should be used with caution.
Avoid the severe damage of liver and kidney.
This product should be kept in a cool and dark dry place. Avoid sunlight.
Do not use a metal container for medicine. Avoid freezing.
WITHDRAWAL TIME
Meat: 28 days. Not to be used in lactating animals.
STORAGE
Seal and store in a dark place below 30°C, should be protected from light.
Keep out of reach of children.
VALIDITY
3 years.
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Penicillin G Procaine and Dihydro...
2024-05-14
KX-PENSTREP 400
Penicillin G Procaine and Dihydrostreptomycin Sulphate Injection
COMPOSITION:
Dihydrostreptomycin sulphate 200mg/ml
Penicillin G Procaine: 200 000 u.i./ml
INDICATIONS:
Infections by germs sensitive to penicillin and dihydrostreptomycin: Cattle pyometra, mastitis,
fracture, actinomycetes and leptospira infection etc.
And diarrhea, metritis, sepsis, cystitis, cattle hemorrhagic septicemia, calf pneumonia, pig
lung disease, fowl cholera, swine brucellosis, concentrations of the equine sepsis, foal
pneumonia, tuberculosis etc.
DOSAGE & ADMINISTRATION:
Intramuscular injection.
General dose: 1ml per 25kg bodyweight daily for 3 to 4 days.
The dose may be doubled for serves cases.
CONTRA-INDICATIONS:
Hypersensitivity to penicillins, aminoglycosides or procaine, renal failure, hearing disorders.
DRUG INTERACTIONS:
Heavy metal especially copper, zinc, mercury, alcohols, acids, iodine, oxidizing agents,
reducing agents, carboxyl compounds, etc., can destroy the activity of penicillin.
No mixed with Chlorpromazine hydrochloride, lincomycin hydrochloride, noradrenaline
bitartrate, oxytetracycline hydrochloride, tetracycline hydrochloride, etc. will produce turbid,
flocculus, precipitation.
SPECIAL WARNING:
Allergic reactions are possible. Pain and tissue reactions may occur with IM or SQ injections.
Free procaine in the formulation may elicit a CNS reaction after injection in some horses.
WITHDRAWAL TIME:
Cattle, sheep, goats and pigs: 18 days Milk: 72 hours
STORAGE:
Sealed and store in a dry place. Keep out of reach of children.
VALIDITY:
3 years.